New ways of imaging with shaped light can lead us to take images of large biomedical objects (eg tissue, small organs) at high resolution with minimal exposure to light, meaning less damage and faster image acquisition, and allow us to see through scattering material such as tissue.

Light Sheet Microscopy

In light sheet microscopy, we illuminate samples with a broad sheet of light rather than point by point scanning. This leads to faster image acquisition and lower sample exposure, thus leading to less “light” damage”. Such imaging can lead to new insights for studies in neuroscience, diseases of the mind (dementia) and developmental biology. In turn this may shed light on numerous biological processes including the development of disease. In particular, we harness the non-diffracting properties of Airy beams in our light sheet microscopes to increase the field of view deeper into the sample.

TRAFIX Microscopy